Detalhe da pesquisa
1.
Phosphorylation of NLRC4 is critical for inflammasome activation.
Nature
; 490(7421): 539-42, 2012 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22885697
2.
FX knockout CHO hosts can express desired ratios of fucosylated or afucosylated antibodies with high titers and comparable product quality.
Biotechnol Bioeng
; 114(3): 632-644, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27666939
3.
Non-canonical inflammasome activation targets caspase-11.
Nature
; 479(7371): 117-21, 2011 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22002608
4.
Pannexin-1 is required for ATP release during apoptosis but not for inflammasome activation.
J Immunol
; 186(11): 6553-61, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21508259
5.
Concurrent transfection of randomized transgene configurations into targeted integration CHO host is an advantageous and cost-effective method for expression of complex molecules.
Biotechnol J
; 16(4): e2000230, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33259700
6.
UBR E3 ligases and the PDIA3 protease control degradation of unfolded antibody heavy chain by ERAD.
J Cell Biol
; 219(7)2020 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32558906
7.
Insulin degrading enzyme (IDE) expressed by Chinese hamster ovary (CHO) cells is responsible for degradation of insulin in culture media.
J Biotechnol
; 320: 44-49, 2020 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32526262
8.
Endothelial intercellular cell adhesion molecule 1 contributes to cell aggregate formation in CHO cells cultured in serum-free media.
Biotechnol Prog
; 36(3): e2951, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31846224
9.
Utilizing a regulated targeted integration cell line development approach to systematically investigate what makes an antibody difficult to express.
Biotechnol Prog
; 35(2): e2772, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30592567
10.
Supplementation of Nucleosides During Selection can Reduce Sequence Variant Levels in CHO Cells Using GS/MSX Selection System.
Biotechnol J
; 13(1)2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28745430
11.
Beating the odds: The poisson distribution of all input cells during limiting dilution grossly underestimates whether a cell line is clonally-derived or not.
Biotechnol Prog
; 34(3): 559-569, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28941017
12.
Taming hyperactive hDNase I: Stable inducible expression of a hyperactive salt- and actin-resistant variant of human deoxyribonuclease I in CHO cells.
Biotechnol Prog
; 33(2): 523-533, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28127892
13.
Slashing the timelines: Opting to generate high-titer clonal lines faster via viability-based single cell sorting.
Biotechnol Prog
; 32(1): 198-207, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26587808